Do you need RNase stable RNAs? Circularize them! The structure is maintained and often the dynamics too. AND – plot twist – if not, than you find that the otherwise boring A-form RNA helices actually have a function: Long-distance transport of dynamic information, otherwise called Allostery. Congrats Katja and Henry!!
We are happy to welcome a new M.Sc. student to our lab: Julian Fischer from Goethe University (Frankfurt, Germany). Welcome!
Imagine if one of RNA’s most common 3D contacts could switch off and on. In our preprint, we identified the A-minor switch that can reversibly “escape” their tertiary contacts, revealing a dynamic regulatory layer in RNA structure (shown by NMR & Cryo-EM and assayed in ribosomes). Read more: https://www.biorxiv.org/content/10.64898/2026.05.08.718354v1
Enabling 1H R1ρ NMR measurements even when NOE’s are present allowed us to identify one more excited state in the Hoogsteen to Watson-Crick-Franklin equilibrium. Have a look here!
We are happy to welcome Adetutu Oyinloye to the lab as a new Erasmus internship student. She will work on microRNA targeting. Welcome!
We are happy to announce that our work recently got published in PNAS. In this study, we introduce a method to boost the sensitivity of RNA NMR by attaching a special spin label (AsymPol) directly to RNA. This enables selective signal enhancement, opening possibilities for studying RNA structure and function even at very low concentrations. Read more: https://doi.org/10.1073/pnas.2531087123
We are also currently looking for a motivated postdoc to explore RNA regulation, microRNAs and RNA dynamics in a supportive, international research environment. Read more here! Application deadline: February 23, 2026
We are currently searching for a highly motivated PhD student to join the project Cellular Structural biology/Biophysics focused on RNA structural dynamics and regulation inside living cells. Read more here! Application deadline: February 20, 202
We are happy to welcome Moa Hedman and Tilde Eklöf as new B.Sc. students to our lab. They will work on microRNA targeting. Welcome!