Welcome Julian!
We are happy to welcome a new M.Sc. student to our lab: Julian Fischer from Goethe University (Frankfurt, Germany). Welcome!
New preprint: The A-minor Switch!
Imagine if one of RNA’s most common 3D contacts could switch off and on. In our preprint, we identified the A-minor switch that can reversibly “escape” their tertiary contacts, revealing a dynamic regulatory layer in RNA structure (shown by NMR & Cryo-EM and assayed in ribosomes). Read more: https://www.biorxiv.org/content/10.64898/2026.05.08.718354v1
HG / WCF equilibrium just got even more exciting
Enabling 1H R1ρ NMR measurements even when NOE’s are present allowed us to identify one more excited state in the Hoogsteen to Watson-Crick-Franklin equilibrium. Have a look here!