About us

Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.


Welcome David!

Dr. David Kosek has joined our lab as Postdoctoral Fellow coming from our collaborator Prof. Emma Andersson to continue to share his expertise on microRNA regulation with the lab!

Congratulations on the defense Lara!

Dr. Sweetapple successfully defended her thesis on 18th of June with her opponent Prof. Qi Zhang from the University of North Carolina! Huge congratulations for a great work, clear presentation and engaging discussion. Her thesis: “A biophysical symphony: the interplay of factors determining microRNA-34a activity” has helped towards deciphering the complicated structural influences on microRNA…

Goodbye Snorri and Marco!

Visiting Professor Snorri Sigurdsson from the University of Iceland is now returning home after a great time with us. We want to thank him for his good humour, expertise, and contributions to our lab discussions – with an exciting collaboration which made significant steps during his stay. Furthermore, a big goodbye and thank you to…

Congrats Rubin!

Congrats Rubin on his article Elucidating microRNA-34a organisation within Human Argonaute-2 by NMR now available at bioRxiv.

Congrats Lara!

Congrats Lara on her article Biophysics of microRNA-34a targeting and its influence on down-regulation now available at bioRxiv.

Job announcements: 5 positions available!

The new Center of Excellence “Chemical Mechanisms of Life”, headed by 4 research groups including ours, is looking for 4 Postdocs and 1 Research Coordinator. Don’t miss this fantastic opportunity to work with us, and apply now!  

Visit our News archive

Contact Karolinska Institutet:

Department of Medical Biochemistry and Biophysics (MBB)

Box 23 109 Karolinska Institute SE-104 35

Stockholm, Sweden



Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics

Solnavägen 9

171 65 Solna

NMR lab:

SciLifeLab Karolinska Institutet

Tomtebodavägen 23b

171 65 Solna

Contact Uppsala University:

Petzold Lab

Dept. of Medical Biochemistry and Microbiology (IMBIM)

D9:3 BMC, Uppsala University 

Husargatan 3

752 37 Uppsala