Congrats Rubin and Walter!
Congratulations Rubin and Walter for their publication in NAR studying the previously unseen arrangement of key nucleotides in the human Argonaute 2 miRNA-mRNA complex
Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.
News
Congrats Henry and Reiner!
Congrats Henry and Reiner for their article in JBNMR on optimising in-cell NMR for nucleic acids!
Welcome David!
Dr. David Kosek has joined our lab as Postdoctoral Fellow coming from our collaborator Prof. Emma Andersson to continue to share his expertise on microRNA regulation with the lab!
Congratulations on the defense Lara!
Dr. Sweetapple successfully defended her thesis on 18th of June with her opponent Prof. Qi Zhang from the University of North Carolina! Huge congratulations for a great work, clear presentation and engaging discussion. Her thesis: “A biophysical symphony: the interplay of factors determining microRNA-34a activity” has helped towards deciphering the complicated structural influences on microRNA…
Goodbye Snorri and Marco!
Visiting Professor Snorri Sigurdsson from the University of Iceland is now returning home after a great time with us. We want to thank him for his good humour, expertise, and contributions to our lab discussions – with an exciting collaboration which made significant steps during his stay. Furthermore, a big goodbye and thank you to…
New project assistant position available!
Want to join our lab to work on ribosome dynamics? We have a project assistant position open with deadline 8th of June.
Congrats Katja!
Work with our visiting Professor Christina Thiele is now available on ChemRxiv.
Congrats Rubin!
Congrats Rubin on his article Elucidating microRNA-34a organisation within Human Argonaute-2 by NMR now available at bioRxiv.
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Contact Karolinska Institutet:
Department of Medical Biochemistry and Biophysics (MBB)
Box 23 109 Karolinska Institute SE-104 35
Stockholm, Sweden
delivery/visit:
Biomedicum:
Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics
Solnavägen 9
171 65 Solna
NMR lab:
SciLifeLab Karolinska Institutet
Tomtebodavägen 23b
171 65 Solna
Contact Uppsala University:
Petzold Lab
Dept. of Medical Biochemistry and Microbiology (IMBIM)
D9:3 BMC, Uppsala University
Husargatan 3
752 37 Uppsala