About us

Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.

Postdoc position available!

We are also currently looking for a motivated postdoc to explore RNA regulation, microRNAs and RNA dynamics in a supportive, international research environment. Read more here! Application deadline: February 23, 2026

PhD position available!

We are currently searching for a highly motivated PhD student to join the project Cellular Structural biology/Biophysics focused on RNA structural dynamics and regulation inside living cells. Read more here! Application deadline: February 20, 202

Welcome Moa and Tilde!

We are happy to welcome Moa Hedman and Tilde Eklöf as new B.Sc. students to our lab. They will work on microRNA targeting. Welcome!

Uppsala will become a NORDSTRUCT hub!

We’re happy to announce that we and our colleagues at Uppsala University are a part of NORDSTRUCT – a project which just received funding from NordForsk to establish a Nordic Research Infrastructure Hub for structural biology over the next four years! Read more here: https://www.nordforsk.org/projects/nordic-research-infrastructure-hub-structural-biology-nordstruct

Congratulations to Joanna and Rubin!

Congratulations to Joanna and Rubin for their latest paper, in collaboration with the Aguilo Lab, which has just been accepted for publication in Cancer Letters! The study uncovers a complex interplay between FBL, rRNA 2′-O-methylation, and RPS28 in shaping the translation of specific oncoproteins and ribosomal composition in triple-negative breast cancer.Well done to everyone involved!

Welcome Aliki!

We are happy to welcome Aliki Karafotia as a new M.Sc. student to our lab. Welcome!

New preprint!

We are excited to share our new preprint on bioRxiv! In this study, we identify a new intermediate in WCF to HG transition and show that 1H R1ρ can be used even when NOE’s are present. Read more: https://www.biorxiv.org/content/10.1101/2025.10.03.677141v1

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Contact

Petzold lab at BMC (D9:3)

Uppsala University

Department of Medical BIochemistry and Microbiology (IMBIM)

Husargatan 3

752 37 Uppsala

Sweden

Delivery address

Katja Petzold

Uppsala University, BMC D9:3

IMBIM

Husargatan 3

752 37 Uppsala

Sweden