Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.
Congratulations to Elnaz Banijamali, Magdalena Riad and Judith Schlagnitweit! Together they have contributed to elucidating the structure of the 5’UTR of the Covid-19 RNA genome, as part of the Covid19-NMR consortium. The paper was marked by the editors as Breakthrough in the journal Nucleic Acid Research.
Hannes Feyrer has received the KI travel grant to perform work on in-cell NMR using DNP together with the Pell lab at the CRMN Lyon, France.
Sabrina Töws does her undergraduate internship with us supported from Erasmus. Sabrina is currently a Master Student in Molecular Medicine at the Goethe University Frankfurt, Germany.
Hampus Karlsson got selected to present his work on ribosome dynamics on the young researcher forum of the ICMRBS. We are excited!
Dr. Lorenzo Baronti has defended his thesis with flying colors as the first PhD student finishing his studies from our lab. Lorenzo helped building the lab to its current glory AND first authored a Nature paper! Congratulations and we wish you an even brighter future.
Christian Steinmetzger, who did his PhD in the lab of Claudia Höbartner, and Natalia Galindo Riera, who did her PhD in the lab of Isabel Martinez Garay, join as Postdoctoral Fellows the lab. Cenk Onur Gürdap comes back and works with us part-time while pursuing a Master degree at KTH.
Please apply via the online system varbi. Join a diverse team having fun doing RNA structural biology/biophysics in vitro and in the cell.
On Thursday the 30th of July at 4pm CET, Katja will present our research at the webinar organized by ICMRBS & Euromar “Emerging Topics in Biomolecular Magnetic Resonance”. This will be later also available on the youtube channel and is organized by L. Andreas, S. Glöggler, C. Griesinger, M. Hong, O. Millet, A. Palmer and M. Zweckstetter.
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Mail:
Department of Medical Biochemistry and Biophysics (MBB)
Box 23 109 Karolinska Institute SE-104 35
Stockholm, Sweden
Biomedicum:
Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics
Solnavägen 9
171 65 Solna
NMR lab:
SciLifeLab Karolinska Institutet
Tomtebodavägen 23b
171 65 Solna
