Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.
Postdoc Ileana Guzzetti received an invitation to discuss how computers and mathematicians can describe and understand dynamics in RNA “Mathematics and Computer Science in Modeling and Understanding of Structure and Dynamics of Biomolecules” (http://www.birs.ca/events/2019/2-day-workshops/19w2257) in Canada. Congratulations!
Hannes Feyrer has been selected to present his research at the conference for Advanced Isotope Labeling Methods for Integrated Structural Biology (link https://www.ailm2019.org) in March in beautiful Grenoble.
The Foundation for Strategic Research has made a great work of art (aka a movie: https://youtu.be/a6jRXKbizlU) highlighting what we are doing in the lab all day.
The Swedish Research Council has awarded our lab funding (link for this: https://ki.se/en/mbb/the-swedish-research-councils-consolidator-grant-of-12-million-to-katja-petzold) for 6 years to study ribosome dynamics and find new drug targets
On Monday the 7th of January, the lab had its five year anniversary. The time has been exciting, with building up two labs and a complete move, many students joining the lab, some are already of to their own research groups. Members of the Petzold Lab have been extra-ordinary successful curious. We got a lot…
Raluca Munteanu is continuing her studies in the Biomedical Program at KI and Noah Hopkins, though still will come to the lab in holidays, has started the IT program, after having designed and worked on many scripts in our lab. Good luck!
Hampus Karlsson has successfully passed his half-time seminar on e.coli ribosome dynamics of h44. Congratulations!
Email: katja.petzold@ki.se Mail: Department of Medical Biochemistry and Biophysics (MBB) Box 23 109 Karolinska Institute SE-104 35 Stockholm, Sweden
Biomedicum: Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics Solnavägen 9 171 65 Solna NMR lab: SciLifeLab Karolinska Institutet Tomtebodavägen 23b 171 65 Solna
