Pure RNA in bucketloads
Congratulations Hampus to the acceptance of His manuscript A robust and versatile method for production and purification of large-scale RNA samples for structural biology in the journal RNA.
Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.
News
Covid19-NMR
We are happy to join the efforts to solve all RNA and protein structures of COVID-19 by NMR (which have not been possible to solve by other methods) and search for drugs fighting this Coronavirus and the disease it causes.
Welcome Walter!
Walter Becker joins our lab as postdoctoral Fellow. He will bring expertise in protein NMR and sample preparation to the lab. See our current people webpage
We are looking for Postdocs
Are you interested in inter-disciplinary research and have a background in Molecular Biology or knowledge of NMR. Please apply via our online system varbi. Apply here.
Covid-19 times
WFH and NMR – team work in trying times: Judith, Hampus and Luca with help from Clara. Stay safe and wash hands!
Welcome Henry
Henry Annecke joins the lab to perform his Master Thesis
Making RNA fast and cheap @Molecules
Congratulations to Hannes for his paper being accepted on how to make “IVT RNA using RNaseH”! Link to paper here.
Katja receives the Wallenberg Academy Fellow
The Knut och Alice Wallenberg foundation awarded funding for 5 years with the prestigious WAF grant to study in-cell NMR of nucleic acids.
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Contact:
Mail: Department of Medical Biochemistry and Biophysics (MBB) Box 23 109 Karolinska Institute SE-104 35 Stockholm, Sweden
Delivery/visit:
Biomedicum: Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics Solnavägen 9 171 65 Solna NMR lab: SciLifeLab Karolinska Institutet Tomtebodavägen 23b 171 65 Solna
