News & Views about our paper
François Major writes “From transient recognition to efficient silencing: a RISCky business” in NSMB. Fabulous!
Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.
News
microRNA dynamics influence activity
Our paper on how miR-34a influences the activity of Sirt1 (regulator of P53) is published in Nature. Congratulations to Lorenzo, first author of the study, and of course everyone else.
Good bye and good luck Sarah
Postdoctoral fellow Sarah Friebe Sandoz finishes her postdoc
in the Petzold lab and leaves for a position in a start up company.
We wish you good luck and we will miss you.
Pure RNA in bucketloads
Congratulations Hampus to the acceptance of His manuscript A robust and versatile method for production and purification of large-scale RNA samples for structural biology in the journal RNA.
Covid19-NMR
We are happy to join the efforts to solve all RNA and protein structures of COVID-19 by NMR (which have not been possible to solve by other methods) and search for drugs fighting this Coronavirus and the disease it causes.
Welcome Walter!
Walter Becker joins our lab as postdoctoral Fellow. He will bring expertise in protein NMR and sample preparation to the lab. See our current people webpage
We are looking for Postdocs
Are you interested in inter-disciplinary research and have a background in Molecular Biology or knowledge of NMR. Please apply via our online system varbi. Apply here.
Covid-19 times
WFH and NMR – team work in trying times: Judith, Hampus and Luca with help from Clara. Stay safe and wash hands!
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Contact:
Mail:
Department of Medical Biochemistry and Biophysics (MBB)
Box 23 109 Karolinska Institute SE-104 35
Stockholm, Sweden
Delivery/visit:
Biomedicum:
Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics
Solnavägen 9
171 65 Solna
NMR lab:
SciLifeLab Karolinska Institutet
Tomtebodavägen 23b
171 65 Solna
