One-pot sample preparation and 1H R1ρ setup visualized
Congratulations Hannes and Judith on their protocol “Practical Aspects of Sample Preparation and Setup of 1H R1ρ Relaxation Dispersion Experiments of RNA”, now available as video too!
Our research group is interested in understanding how RNAs change their structures in order to perform function. Until recently, only snapshots of molecules could be observed, hiding their mode of operation. We employ Nuclear Magnetic Resonance (NMR), and other biophysical techniques, to investigate the molecular mechanism of RNA function. When function of these molecular machines becomes apparent, it also provides a variety of unique new drug targets. The lab develops methods in NMR and RNA biochemistry to address these questions. Current projects include viral, bacterial and eukaryotic regulatory RNAs, e.g. microRNAs, ribosomal RNAs or RNA from HBV.
News
Welcome Joanna!
We’re welcoming our new postdoctoral fellow Joanna who is joining us after a postdoctoral fellowship at the Medical University of Warsaw, Poland.
Congratulations Rubin
Congratulations to Rubin Dasgupta for being selected to present his PhD work on “deciphering the paramagnetic NMR spectra of small laccase” at the ICMRBS Early Career Researcher Webinar Series. See here: https://njfowler.com/icmrbs
Congratulations Juliane!
Juliane successfully finished her master thesis in the group and we wish her all the best for the future!
Making RNA easy
Congratulations Hannes, Hampus, and Lorenzo on their protocol “Production of Structured RNA Fragments by In Vitro Transcription and HPLC Purification”.
Welcome Wei-Tse
Wei-Tse is a first-year bachelor’s student at Karolinska Institute who joins the lab for an internship during the summer
Open Postdoc position(s)
We are looking for people with experience in RNA biochemistry, SHAPE, RNA biophysics, or NMR to join our lab. Please apply here.
Congratulations Dr. Hampus
Good bye and good luck to the talented and newly graduated Doctor Karlsson! We are sure Hampus’ skills will be equally appreciated in Göteborg during his postdoctoral experience there. You will be missed.
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Contact:
Mail:
Department of Medical Biochemistry and Biophysics (MBB)
Box 23 109 Karolinska Institute SE-104 35
Stockholm, Sweden
Delivery/visit:
Biomedicum:
Petzold Lab Quarter 9B, Dept. of Medical Biochemistry and Biophysics
Solnavägen 9
171 65 Solna
NMR lab:
SciLifeLab Karolinska Institutet
Tomtebodavägen 23b
171 65 Solna
